The conventional approach to methylation wasn’t cutting it, so we redefined it

Lab reports matter, but answers often lie deeper: in sleep, stress, nutrition, and unprocessed emotions. We take a different path—research-backed products and lifestyle habits that bio-harmonize your system rather than biohack. Because methylation touches everything including detox, cellular health, and  stress response.
Learn About Methylation Science
the otherway standard

The pillars of methylation health powering our formulations

It takes more than b-vitamins to improve methylation. Our approach embraces the full breadth of methylation, linking detox, cellular repair, mood, and stress resilience into integrated solutions.
1

Neurotransmitters & Mood

How it's Affected

Methyl groups help make serotonin, dopamine, and norepinephrine—key for calm focus and steady mood.

How we support

L-5-MTHF, B12 matched to sensitivity (methyl/hydroxo/adenosyl), P5P; saffron/theanine where helpful.
2

Detox & Antioxidant Defense

How it's Affected

Methylation and glutathione recycling clear daily toxins and ease “wired-but-tired” mornings

How we support

L-5-MTHF, B2/B6, selenium; cordyceps & mushroom allies; choline/betaine as gentler donors.
3

Cellular Energy & Mitochondria

How it's Affected

Efficient methylation supports ATP production—so thinking, moving, and repair feel possible again.

How we support

CoQ10, cordyceps, NAD⁺ precursors/ribose (Source Energy, soon) plus core methyl cofactors.
4

Homocysteine & Cardiovascular Balance

How it's Affected

Methylation and glutathione recycling clear daily toxins and ease “wired-but-tired” mornings

How we support

L-5-MTHF, B12, B6 (P5P), choline/TMG; magnesium for vascular tone.
5

Stress System or HPA Axis

How it's Affected

Chronic stress blunts methylation and cognition; you feel anxious, wired, and sleep poorly.

How we support

Magnesium complex, theanine, adaptogens; methyl-free options for COMT-sensitive brains.
6

Gut–Brain Absorption

How it's Affected

You only benefit from what you absorb; the gut also signals mood and mental clarity

How we support

Bioavailable forms (not cheap synthetics), lion’s mane & phosphatidylserine for clean signaling

See How Well You Are Methylating

Find out your methylation status in 60 seconds

Understand the gaps holding back your energy and mood. Despite your genetics, proper methylating is harder than ever due to the stress, toxins, and poor nutrition in our modern world.
Check Methylation Status

Beyond B-Vitamins

Ingredients that power every pathway

Forms your body actually uses—carefully sourced, precisely dosed.

Folinic Acid

(Not Folic Acid)

Supports DNA repair, neurotransmitter production, and detox by feeding your methylation cycle.

The Otherway Difference

Instead of relying solely on methylcobalamin (which can overstimulate some people), we blend hydroxo and adenosyl forms—clean, stable, and highly effective without the “wired” edge.
Why ours is different+

Hydroxo + Adenosyl B12

Fuels cellular energy, mood balance, and nerve health.

The Otherway Difference

Instead of relying solely on methylcobalamin (which can overstimulate some people), we blend hydroxo and adenosyl forms—clean, stable, and highly effective without the “wired” edge.
Why ours is different+

Magnesium

(Glycinate, Taurate, Malate)

Relaxes muscles, calms the nervous system, and supports mitochondrial energy production.

The Otherway Difference

Instead of relying solely on methylcobalamin (which can overstimulate some people), we blend hydroxo and adenosyl forms—clean, stable, and highly effective without the “wired” edge.
Why ours is different+

Saffron & L-Theanine

(Select Formulas) Supports a calm, uplifted mood and smooth focus without jitters.

The Otherway Difference

Instead of relying solely on methylcobalamin (which can overstimulate some people), we blend hydroxo and adenosyl forms—clean, stable, and highly effective without the “wired” edge.
Why ours is different+
View All Ingredients

We don’t leave quality to chance.

Every formulation we create starts with one truth: your needs aren’t average
1

Clinically studied ingredients, chosen for methylation needs.


Every nutrient we use is backed by human research and selected for how it supports methylation, detox, mood, and energy.

2

Bioavailable forms matched to genetic sensitivity.

We avoid cheap synthetics and choose forms your body can actually convert and use, even if you have reduced enzyme activity.

3

Independent third-party testing for purity and potency.

Every lot is verified for identity, strength, and the absence of heavy metals, mold, or unwanted fillers—critical for sensitive biochemistry.

4

Precision dosing for the genetically sensitive.

No megadoses that trigger crashes—just the right amount for sustained, balanced impact.

5

Responsibly and traceably sourced.

 From regenerative farms to verified growers, our supply chain is transparent, clean, and ethical.

6

Manufactured for consistency, every time.

Made in the USA under cGMP standards so each capsule delivers what your body needs, no surprises.

Science That Puts You Back in Control

Epigenetics proves your genes are not your destiny. Methylation is one way to change the story.

Your biology is adaptable. Explore clear, credible research on methylation, MTHFR, and the ingredients we use—so you can see exactly why our formulas work.
Read Pathway Journal
Dr. Kara Fitzgerald, ND
“Methylation is one of the most powerful levers we have to influence gene expression — it’s how lifestyle and nutrition literally talk to your DNA.”
Dr. Kara Fitzgerald,
ND

Formulas Designed for Methylation

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Insights & stories to guide your methylation journey

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